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Phosphorylated tau-217 in blood has shown promising accuracy in detecting AD pathology 9

Therefore, blocking the HMGB1-AGER pathway with small molecules or genetic methods could limit the inflammatory response mediated by ferroptosis ( Radiotherapy Radiotherapy can directly cause oxidative damage to lipid membrane, leading to the accumulation of toxic lipid peroxidation and triggering ferroptosis in cancer cells

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Chronic low-grade inflammation, often referred to as inflammaging, has been associated with alterations in the ovarian microenvironment, potentially affecting follicular development and oocyte maturation [67]