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Seidel et al., 2013

Abbreviations: ALT alanine transaminase CYP the cytochrome P450 INR international normalized ratio References [1] Kur P, Kolasa-Woosiuk A, Misiakiewicz-Has K, Wiszniewska B

Additionally, the ability of FR to internalize relatively large molecules renders it suitable for developing targeted therapies ( 2 Folate transporter proteins Humans cannot synthesize folate, an essential vitamin for eukaryotic cell proliferation and differentiation, and must obtain folate from dietary sources ( Figure 1 )