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doi: 10.1152/physrev.00034.2015 30

The glutathione-consuming activity of the methylglyoxal pathway enables glucose utilization and aerobic respiration, while bolstering resistance of Salmonella to the antimicrobial actions associated with oxidative products generated by the phagocyte NADPH oxidase in the innate host response of macrophages and mice

Furthermore, we took into account that the glutathione moiety that originates from the GSSR disulfide substrate might be sandwiched between the protein and the glutathione moiety of GSH approaching the active site (Fig

We also thank the Biomedical Research Unit and Biomedical Research Core of Tohoku University Hospital and Biomedical Research Core of Tohoku University Graduate School of Medicine for technical support