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In OA research, recent evidence indicates that pharmacological activation of the Nrf2GPX4 signaling axis using bioactive natural products or synthetic small molecule agonists can effectively mitigate ferroptosis in vitro cultured chondrocytes and in vivo OA animal models, while significantly suppressing ECM degradation progression (Wu et al., 2025b

Sun Y, Li Y, Zong Y, Mehaisen GMK, Chen J

In addition, the measure steward has successfully deployed its software across a diverse range of several hundred clinical settings with varied EHR, Picture Archiving and Communication System (PACS), Radiology Information System (RIS), dose monitoring, image quality, and CMS measure submission systems

10.1016/j.tranon.2021.101314 66 XuM.ZhangD.YanJ