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doi: 10.1016/j.molcel.2017.12.021 37 ReniereM

Consistent with these conclusions, the expression of ferroptosis-related factors in DN cells is unbalanced, accompanied by a significant increase in the HGMB1 level

These studies often used doses ranging from 250mg to 500mg per day

Researchers investigate its role as a cofactor for glutathione peroxidase and S-transferase enzymes, and examine its involvement in xenobiotic metabolism and heavy metal chelation pathways in cell cultures