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The predicted binding mode of 1j indicates the C5-amino substituent forms hydrogen bonding interaction with the carboxylic backbone of the Ser201 residue and a hydrophobic bonding with the Ser213 residue unlike the NCA amide group that is in hydrogen bonding distance from with the NNMT Ser213 residue

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Argireline: The Topical Botox Myth Vs Real Effects Argireline, also known as acetyl hexapeptide-8, is frequently marketed as a topical alternative to injectable neuromodulators

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