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Cagrilintide has shown promising results in animal studies and clinical trials, demonstrating significant weight loss and improved glycemic control in obese patients with or without type 2 diabetes

The a-DG-AuNPs induce the formation of micrometric bubbles when excited for 1.26 s at 760 nm with pulsed laser at power of 24 W/cm 2 because of NIR radiation harvesting of the fluorophore at laser power close to that observed for gold nanorods

Therefore, ATRA-ATO-NPs could greatly enhance the synergistic inhibition of ATRA and ATO on PIN1 expression in cancer cells, consistent with the above experimental results

This work was financially supported by the Medical University of Biaystok (B.SUB.23.325 to TD)