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Transl Cancer Res (2020) 9(5):3499506

While ex vivo organ culture uses real human tissue, it cannot fully replicate conditions on a living scalp including skin absorption, blood supply, hormonal influences, and the immune system

The components of the TCA cycle serve as precursors for the synthesis of non-essential amino acids, which account for more than 50% of protein carbon (Roberts et al., 1953)