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In order to adapt to these special environments, animals during the ice age underwent significant adaptive changes in physiology, morphology, and behavior

This is especially true if you are a vegan, are older than age 50 and of African American or Northern European descent, have an autoimmune disorder, or have had your stomach removed

Other malabsorption causes include: Atrophic gastritis and reduced gastric acid production (common in older adults) Gastrointestinal surgery, particularly gastrectomy, ileal resection, or bariatric surgery (especially gastric bypass) Inflammatory bowel disease affecting the terminal ileum (Crohn's disease) Coeliac disease and other small bowel disorders Chronic pancreatitis affecting enzyme secretion Helicobacter pylori infection (may contribute to reduced absorption) Medication-related deficiency is increasingly recognised