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A group receiving annual administrations of both peptides for six years saw a 4.1-fold reduction in mortality compared to controls, highlighting their potential research interest in the context of prolonged active longevity

Early studies revealed that the neuropeptides delivered orally in this way had a pharmacodynamic profile consistent with the reported pharmacology, were rapidly absorbed by the gastrointestinal tract, and reached concentrations several-fold higher than those seen naturally postprandially (128)

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Injection site reactions including minor redness, itching, or irritation occur occasionally