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For mild pigmentation, dermatologist-prescribed creams (with ingredients like kojic acid, niacinamide, arbutin, and retinoids) may be used to fade dark patches over time

GenBank AA305308 EST176312 Colon carcinoma (Caco-2) cell line II Homo sapiens cDNA 5' end similar to ribosomal phosphoprotein P0, acidic, mRNA sequence

Poh-Fitzpatrick MB, DeLeo VA

In contrast to its pro-inflammatory role in myeloid cells, NF-B has a protective role in intestinal epithelial cells, where it is required for maintaining epithelial integrity and intestinal immune homeostasis