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It is a peptide that has been studied for possible effects on sleep regulation, especially deep sleep or delta-wave sleep

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In a small, randomized, double-blind placebo-controlled crossover trial assessing the effectiveness of lisdexamfetamine for attentional deficits associated with moderate-to-severe TBI, improvements in measures of sustained attention, working memory, and executive functioning were identified 8

It is also associated with increased blood pressure and risk of hypertension, which is responsive to riboflavin supplements (44)