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Therefore, our findings stimulate new investigations regarding the response of other antioxidant parameters, such as the antioxidant enzymes superoxide dismutase (SOD), responsible for converting the superoxide anion (O 2 ) into hydrogen peroxide (H 2 O 2 ), and catalase (CAT), responsible for removing H 2 O 2

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Indeed, in one hand, their activation is involved in neuroinflammation which endanger neurons via cytokines overproduction and on the other hand, atrophy and loss of activity leads to reduced neuronal protection (Rodrguez-Arellano et al., 2016

Microsomal glutathione S-transferases: selective up-regulation of leukotriene C4 synthase during lipopolysaccharide-induced pyresis