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The NO/VEGFR2/Akt-eNOS Pathway One of the most frequently cited mechanisms involves the nitric oxide (NO) signaling pathway and vascular endothelial growth factor receptor 2 (VEGFR2)

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It activates pathways such as ERK1/2 and FAK-paxillin, which are involved in cell growth and migration

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A landmark 2003 study in the Journal of Physiology and Pharmacology examined rats with completely transected Achilles tendons

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