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In this complex, the cereblon is the unit responsible for recognizing and binding to target proteins for subsequent ubiquitination, while the DDB1 protein functions as a support linking cereblon to the Cullin4A/4B proteins, which in turn serve as molecular scaffolds 33,41

10.1146/annurev.pa.25.040185.003435 3

Furthermore, emerging evidence suggests that excessive, long-term consumption of prebiotics and probiotics, especially in capsule form, might lead to issues like brain fog