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Description

Cell 160 , 10611071 (2015)

In each case, the rebinding of dissociated nascent peptide/DNA or peptide/RNA complex is prevented, and with increasing time, nascent peptide/DNA or peptide/RNA complexes of higher and higher affinity are recovered

During the activation stage, ROS can promote the assembly and activation of the NLRP3 inflammasome, and thioredoxin-interacting protein (TXNIP) plays an important role in this process