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62 Brain biochemistry, metabolism, and functions, including glucose uptake and energy consumption, oxidative tissue stress, cholinergic deficiency, and cognitive capacities, are severely and persistently impacted by ICV treatment with STZ

CHESSA L

The water temperature was maintained between 26 and 28 C with aeration, and 10% of the water was replaced daily with fresh water

Suicide risk is high due to poor quality of life, with one example of a patient completely bed-bound for years who felt isolated, struggled with severe exhaustion and pain, often unable to speak or have the cognitive energy to focus, consequently deciding to end her life [19]