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"Theres one thing you can change to stop aging your brain and putting yourself at increased risk of dementia, and thats to quit smoking." One positive finding was that kicking the habit can prevent the loss of additional brain tissue but the shrinkage cant be reversed

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PKC activation reduces amiloride-sensitive epithelial sodium channel (ENaC) expression, which is important for alveolar fluid clearance (AFC) and results in enhanced lung edema and worsened lung function [47]