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In addition, these workers found that antidepressant treatment may lead to defective spindle assembly and altered organelle distribution, with changes in the protein concentrations of small C-terminal domain phosphatases-1 and -3, nuclear mitotic apparatus (NuMa), and calnexin occurring during cell division in vitro

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The samples were homogenized to allow for centrifugation of the supernatant, followed by measurement of AngIV, TNF-alpha, IL-10, and IL-1-beta levels through the use of a sensitive and specific ELISA assay

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