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Statin therapy increases lipoprotein(a) levels

It enhances the protein stability of pluripotency factors by binding to pluripotency factors and recruiting the deubiquitinating enzyme USP7, thus preserving stem cells' selfrenewal ability

Most of glutathione-related metabolism, including pathways such as glutathione metabolism, D-glutamine and D-glutamate metabolism, arginine and proline metabolism, arginine biosynthesis, glyoxylate and discarboxylate metabolism, alanine, aspartate and glutamate metabolism, histidine metabolism, cysteine and methionine metabolism, and glycine, serine and threonine metabolism, showed enhanced expression during the lag and log phases in all strains (Fig

Furthermore, glycogen degeneration of distal tubules, fatty degeneration of glomerular endothelium and hypertrophy of glomeruli and mesangium were observed in the kidneys of the diabetic animals when histopathological evaluation was performed at 4, 8, and 15 weeks (glomerular and mesangial hypertrophy were observed only at 15 weeks)