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By enhancing the integrity of granulosa cell layer and reducing educe prevalence of atresic follicles and follicular cysts, resveratrol promotes the transition of follicles from the preantral to antral stage, facilitating the development and maturation of dominant follicles (109)

Further research would be promising to find microbiology-based biomarkers for the diagnosis or treatment

In fact, Kokou et al (2018) conducted an experiment in which they performed transgenerational selective breeding cold tolerance in tropical tilapias and concluded that the microbiomes of cold-resistant fish showed higher resilience to temperature changes, indicating that the microbiome is shaped by its hosts selection

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