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258,259 In senescent cells, the mitochondrial fission increases, causing the increase of dysfunctional mitochondria

Fang Zhu, Department of Entomology and Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA

Increased levels of lipid ROS and upregulated ferroptosis-related protein expression, which further led to an increase in the type collagen II expression and a decrease in the MMP-13 expression, were also observed under these conditions