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To achieve this, ES cells have higher antioxidant defense mechanisms, resulting in a lower mutational frequency than differentiated cells [119, 120]

The 24-month survival rate reached 54%, and treatment-related grade 35 adverse events occurred in only 9.5% of patients, indicating a favorable safety profile

In laboratory studies, TB-500 has been evaluated for its interaction with actin-binding pathways, cytoskeletal organization, and cellular migration processes