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The mechanism involves upregulation of growth hormone receptors in tendon fibroblasts and increased collagen synthesis at the repair site

Epitalon, also known as epithalamin or epithalon, is a synthetic tetrapeptide composed of Ala-Glu-Asp-Gly, derived from a naturally occurring pineal gland extract called epithalamin

Then the mixture was centrifuged at 5 000 g for 10 min, and the supernatant was pipetted in separate tubes containing freshly prepared 9% ascorbic acid