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Additionally, AOD-9604 does not stimulate IGF-1 production or activate growth hormone receptors, pathways that would otherwise affect appetite-regulating neuropeptides

Through effectively attenuating the redox-active Fe 2+ accumulation, decreasing the ferroptotic changes, enhancing the Nrf2-mediated anti-oxidative enzymes expression, reducing the production of key inflammatory factors, and suppressing the caspase 3-dependent apoptotic signaling, ALA remarkably protect the liver function and prevent CSD-induced metabolic deficiency (Figure 7)

Selected Data 1) The research study conducted by the research team of Kwon and Park aimed to evaluate the protective effects of the peptide AOD9604 when administered via intra-articular injection on cartilage in a collagenase-induced osteoarthritis (OA) rabbit model