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doi: 10.4314/biokem.v16i2.32574 124 OlubiO.Felix-MinnaarJ

K.TakaharaS

One patient permanently discontinued study therapy because LVEF dropped from 70% at baseline to 24% after nine cycles and did not improve to more than 50% within 4 weeks of treatment interruption

Evidence suggests that RGD enhances cell attachment and spreading of osteoblasts onto scaffolds and graft material [140, 141, 159, 188] whilst increasing cellular proliferation and the expression of ALP, Runx2, osteocalcin, osteopontin and bone sialoprotein [141, 142, 146, 190, 191]