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They concluded that B12 accumulation in the placenta may represent an important factor in providing sufficient amount of this essential nutrient to the fetus (Giugliani, 1985). Due to a lack of clinical trials and case reports examining non-daily doses of B12 in pregnant or breastfeeding women, perhaps non-daily injections can provide some insight

QIAGEN RNeasy Mini Kit (QIAGEN, Germany) was used to extract total RNA

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This proves that the effects of this micronutrient depends to a great extent on its levels of it in the organism [7]