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n = 36 placebo)

Importantly, along with an induction of HIF1, in SCD erythroblasts cultured in the absence of hemin, we detected a significantly decreased CBS expression under hypoxia compared to normoxia (Supplementary Fig

(138) published research in Microbiology Spectrum in 2023 finding that methionine, leucine, isoleucine, and valine levels were significantly elevated while acetate levels were decreased in DKD patients