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BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia-reperfusion

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plasma radiolabel was detected in naturally occurring polar compounds that included proteins, peptides, and free amino acids (phenylalanine and tyrosine)

Their investigation using SIRT3 knockout mice revealed that the absence of SIRT3 led to increased mitochondrial ROS production and protein carbonylation, markers of oxidative stress and protein damage (Figure 2)