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Description

Maddox EK, Massoni SC, Hoffart CM, Takata Y

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Physiologically based pharmacokinetic modeling and simulation PBPK models were developed for midazolam, dextromethorphan, and mitragynine using the population-based simulator Simcyp (version 22

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2021;320(4):E835-E845

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39 reported no histopathological changes in the brain, spinal cord, and heart upon subchronic exposure to methanol extract

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