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DOI: Publisher Name: Humana Press, Cham Print ISBN: 978-3-319-19095-2 Online ISBN: 978-3-319-19096-9 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)

The release of Nrf2 from Keap1 is also achieved by its phosphorylation on Ser40 by several kinases such as protein kinase C (PKC), casein kinase-2 (CK2), phosphoinositide-3-kinase (PI3K), c-Jun NH 2 -terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and protein kinase RNA-like ER kinase (PERK) (82)

J R Soc Interface 8:13791385

published in the Bulletin of Experimental Biology and Medicine (2011) reported on a 15-year follow-up of a peptide geroprotector from the pituitary gland, with findings supporting Epithalons role in inhibiting rapid aging