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*Correspondence: Jun-Jian Zhang, [email protected] This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

doi: 10.1016/j.eurpsy.2017.03.002 63 GhadirivasfiM.NohesaraS.AhmadkhanihaH

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In total, 8590% of ALS cases are sporadic, occurring without known genetic cause or family history