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The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

While that's substantially higher than the 600mg starting dose we generally favor for people new to NAC, it reflects the GlyNAC protocols studied in healthy-aging research.34 57 58 Some readers may prefer to start with a smaller serving for tolerability, but the clinical research on GlyNAC has generally evaluated gram-level doses of both ingredients, so it's unclear whether substantially lower amounts would provide the same benefits

Prior to introducing the compound into your laboratory workflow, reconstitution must be carried out using an appropriate sterile, non-pyrogenic, or bacteriostatic diluent