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Subsequently, HaCaT keratinocytes viability after treatment with test compounds, GHK, CuCl 2 and Cu(OAc) 2 were assessed using MTT assay and LDH assay

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Dynamic death decisions: how mitochondrial dynamics shape cellular commitment to apoptosis and ferroptosis

185 Moreover, CDK2 inhibitor candidates, e.g., INCB123667 186 (NCT05238922, ClinicalTrials.gov, 2025) and BLU-222 187 (NCT05252416, ClinicalTrials.gov, 2025), have been tested in several ongoing phase I/II clinical trials and exhibited promising anticancer effects in certain types of tumors according to preliminary data