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This should be done with the view to achieving mechanistic insights on specific causative pathways, while well-structured prospective clinical trials should be carried out to establish long-term effectiveness and safety

10.1016/j.redox.2014.02.001 21 KinaciM.ErkasapN.KucukA.KokenT.TosunM

Once produced in cells, its elimination depends mainly on the action of antioxidants like GSH

As single-cell and multi-omics technologies continue to mature, researchers will increasingly be able to profile DNA methylation, histone modifications, chromatin accessibility, and gene expression within the same cell, thereby generating a more accurate picture of epigenetic changes associated with depression and addiction 186,187