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Compared with healthy individuals, those with established insulin resistance or type 2 diabetes might be more susceptible to the detrimental impacts of circadian disturbances on glucose metabolism [44, 45]

SOD is an enzyme that converts superoxide radicals into hydrogen peroxide, which halts the deleterious effects of a radical chain reaction at the initiation stage (88)

the homodimeric antibody thus generated may have increased complement-mediated cell killing and antibody- dependent cellular cytotoxicity (ADCC) (see, e.g., Caron et al

Depending on the nutrient and its dosage, some side effects may occur very quickly, while others may take a longer time to develop ( For instance, taking a very high dose of one or multiple nutrients may cause gut symptoms that generally develop shortly after taking the supplement ( However, more severe side effects may develop over time as excess amounts of nutrients or unwanted contaminants gradually accumulate in the body