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Description

Chugai's medicinal chemistry effort identified a series of non-peptide compounds that activated the GLP-1 receptor with nanomolar potency through a previously unrecognized binding pocket

This shift in perspective also opens new challenges for computational and experimental drug discovery

This paper was not cited in the literature until 2009, and was, interestingly, cited in the context of the potential importance of vaccines, not APAP, in the etiology of ASD [60]