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These results suggest that A deposition can be correlated with the production of lipid peroxides and reduced capacity to store intracellular iron in AD brain organoids

A series of accessory genes, which encode accessory proteins (ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8b, ORF9b and ORF14), lie between these structural genes

Importantly, MAF-derived signaling is amplified under hypoxic conditions 83 , underscoring that stromal cues and physicochemical stressors act synergistically rather than independently