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This may be due to the removal of toxic substances from the bloodstream and the increased production of glutathione, a powerful antioxidant that helps protect cells from damage

Another pathway shown that LPS promotes the expression of Atrogin-1 and MuRF1 genes via MAPK activation, activating both the UPS and autophagy-lysosome pathways, leading to skeletal muscle protein degradation (Ronnebaum et al., 2014)