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These features make it a commonly employed model for investigating the functions and hormonal regulation of granulosa cell [28]

In the central venous area with high blood flow shear stress, NETs-DNA binds to platelet surface GPIIb/IIIa receptors via electrostatic interactions, forming mechanically stable thrombus complexes that exacerbate local circulatory barriers (132, 133)

This is primarily due to the susceptibility of L-glutathione to breakdown in the digestive tract and its difficulty in crossing cell membranes intact

Therefore, the mitigating effect of folic acid on IBD and CRC may be related to the inhibitory effect of folate on ferroptosis