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2 Ferroptosis 2.1 Ferroptosis characteristics Ferroptosis causes cell membrane rupture and blistering, mitochondrial shrinkage, mitochondrial ridge decrease or removal, increased membrane density, and normal nuclear morphology, but there is no chromatin condensation, according to the ultrastructure of the cells

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This indicates that an inflammatory environment has been induced in which the levels of potentially pathogenic cytokines are likely to cause, or contribute to the induction of neuronal damage or death ( It is now clear that there are also major changes in the immune system associated with some central disorders, of which Huntington's disease represents a good example

It is not known if sildenafil caused these problems