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The literature also describes upregulation of growth factors involved in tissue repair, modulation of nitric oxide synthase activity, and effects on the dopaminergic and serotonergic systems that are harder to interpret clinically [Sikiric et al., Inflammopharmacology, 2018]

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51 This shows that the rehabilitation protocol for PRP is less in duration, and this might be considered in the patients preference if the two options can be done

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