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Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress

We hypothesized that age-dependent elevation of labile iron, coupled with a reduction of glutathione levels conspire to lower the threshold for ferroptotic signaling, increasing the vulnerability of aged animals and implying that disruption to the iron-glutathione axis is fundamental to natural ageing and death

The low cost of the older first-generation antipsychotic drugs contributes to their widespread use despite their risk of adverse EPS effects (2)

10.1089/ars.2017.7462 Antioxid Redox Signal