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Cao Y, Cao R, Hedlund EM

No controlled trial has measured its skin effects or established a reliable results timeline

One clinical trial showed that ipamorelin administered to healthy volunteers produced dose-dependent, pulsatile increases in growth hormone concentrations with predictable pharmacokinetics and without serious adverse effects, establishing its ability to stimulate GH release

Huberman notes that NSDR can mimic some of the restorative effects of sleep, making it especially useful for individuals who struggle with sleep deprivation or want to enhance recovery from physical and cognitive exertion