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Administration of PCCs results in rapid hemostasis, similar to that of FFP, namely, with comparable rates of thromboembolic events, but with reduced rates of volume overload

Chen J, Williams S, Ho S, Loraine H, Hagan D, Whaley JM, et al

Moreover, culturing isolated cells without NAD(H) precursors, where the salvage pathway for NAD(H) synthesis is not functional, is predicted to decrease NAD + levels below the physiological requirement

Ding M, Bhupathiraju SN, Satija A, van Dam RM, Hu FB (2014) Long-term coffee consumption and risk of cardiovascular disease: a systematic review and a dose-response meta-analysis of prospective cohort studies