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(2016) 11:e0161571

The siRNA sequences are listed in Tables I and II

Following the Braak theory of ascending pathology from the brainstem towards the cortex, in the PD brain (Braak et al

Pathway enrichment analysis suggested 23 key regulators of the CS response (Supplemental Table S5), including known factors like -catenin 36 , transforming growth factor 1 37 and KRAS 38 , while NUPR1, to the best of our knowledge, had not been described in the context of the airway epithelial response to CS (Fig