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Mitochondrial quality control mechanisms, including mitophagy and fission/fusion dynamics, are essential at this stage to prevent chronic ROS leakage and restore redox homeostasis

Formoso, G

List of studies Overview of EpitalonHighly Bioactive Pineal Tetrapeptide with Promising Properties Type of study: literature review Number of citations: 1 Year: 2025 Authors: Szymon Kamil Araj, Jakub Brzezik, Katarzyna Mdra-Gackowska, ukasz Szeleszczuk Journal: International Journal of Molecular Sciences Journal ranking: Q1 Key takeaways: Epitalon shows significant geroprotective and neuroendocrine effects, with potential mechanisms including antioxidant, neuro-protective, and antimutagenic effects

In this context, there is an emphasis on the need for a deeper understanding of the functions of FOXO in the nervous system, which could lead to the development of targeted research approaches for these severe diseases