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The skills and habits developed during the program are designed to support long term weight management

Saulnier et al., 2013)

In addition, interventions that reduce intrahepatic triglyceride content through modest weight loss or leptin treatment dramatically reverse hepatic insulin resistance in T2DM, NAFLD, and lipodystrophic patients [83]

In contrast, in situ vaccination triggers a robust local inflammatory response that not only primes CTLs but also facilitates epitope spreading, thereby enhancing the breadth and durability of the systemic antitumor immune response