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Additionally, the ECM plays a role in immune cell adhesion and migration (71)

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

[1] [2] This medication works by enhancing insulin secretion, suppressing glucagon release, and slowing gastric emptyingan effect that is most pronounced after initial doses and may attenuate over timeleading to reduced appetite and caloric intake

In addition to the ion combination, based on previous finding that Qu could chelate with some metal ions (e.g., Cu 2+ ) and the chelation further enhanced the biological activity of metal ions [25,27,28], we proposed a combination approach consisting of ion-ion and ion-flavonoid synergetic actions