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DevisscherLVan CoillieSHofmansSVan RompaeyDGoossensKMeulEet alDiscovery of novel, drug-like ferroptosis inhibitors with in vivo efficacy

Mice were kept at 2123 C, in 4060% humidity, and with a 12 h light/12 h dark light cycle

Metformin has anti-inflammatory and immunomodulatory properties in various immune-related diseases through AMPK-dependent and AMPK-independent mechanisms involving both the innate and adaptive immune systems

However, the editing of the genome in the human embryo faces formidable biological obstacles, in addition to ethical and regulatory questions, with the latter having been discussed elsewhere (3)